Exploration into conolidine has resulted in discovery of an opioid receptor in the body referred to as ACKR3/CXCR7. ACKR3 appears to be the most desired target for conolidine, which also disregards the opposite 4 classical opioid receptors(three).Corydalis will be the genus of a perennial flowering plant from the poppy relatives with about 400 spec